Search on: CASPASES, EFFECTOR 
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Descriptor English:   Caspases, Effector 
Descriptor Spanish:   Caspasas Efectoras 
Descriptor Portuguese:   Caspases Efetoras 
Tree Number:   D08.811.277.656.262.500.126.350
D08.811.277.656.300.200.126.350
D12.644.360.075.405.350
D12.776.476.075.405.350
Definition English:   A subclass of caspases that contain short pro-domain regions. They are activated by the proteolytic action of INITIATOR CASPASES. Once activated they cleave a variety of substrates that cause APOPTOSIS. 
Entry Combination - descr/qualif English:   Caspases, Effector/antagonists & inhibitors use Caspase Inhibitors
 
History Note English:   2007 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52220 
Unique Identifier:   D053470 

Occurrence in VHL:
 

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